Archive for Diseases

Help Kids Fight Cancer with Team Jannie

Jannie Harvey is a very special kid. She’s a twin and just at the age of 4 she was diagnosed with Wilms Tumor. Everyone thought that Jannie wasn’t going to survive. They thought that Jannie only had 24 hours or less to live because her heart rate was dropping and the hospital didn’t have enough medications to help her.
However, despite what everyone believed and thought would happen a miracle occurred and Jannie survived and is now a cancer survivor. During that time people helped Jannie with donating and giving as much as they could so she could have the help she needed to survive. The sad news is, there are many other kids like Jannie who also need help.
Currently, we’re seeking sponsors and companies that would be able to give and donate to help children like Jannie who might not have survived if it wasn’t for the kindness of other people. Join in on the fight to help children who have cancer and bring more awareness to it so hopefully a cure can be found soon. Visit http://www.gofundme.com/thefight4kidswithcancer for more information.

Types of Diabetes: Risk Factors and Symptoms

Type 1 Diabetes

In type 1 diabetes, or insulin-dependent diabetes, the pancreas cells which normally produce insulin, are destroyed.

When little or no insulin comes from the pancreas, the body can not absorb glucose from the blood, the cells begin to “starve” and the blood glucose level is constantly high. The solution is to inject insulin subcutaneously (under the skin) so it can be absorbed into the blood. It is not yet possible to produce a form of insulin that can be administered orally since insulin is degraded in the stomach in an inactive form.

Once the disturbance is developed, there is no way to “revive” the insulin-producing cells of the pancreas. The transplantation of a healthy pancreas or only the transplantation of insulin producing cells from a healthy pancreas has been attempted, but are still considered experimental stage. Therefore, the correct diet and treatment with insulin are still needed throughout the life of a diabetic.

It is not known what causes the destruction of insulin-producing cells of the pancreas or why Diabetes appear in certain people or other. Hereditary factors appear to have an important role, but the disorder virtually never directly inherited. Diabetics or people with diabetes in the family, should not have restrictions on having children.

Type 2 Diabetes

Although it is not known what causes Type 2 diabetes, it is known that in this case the hereditary factor has a value much greater than in Type 1 Diabetes. There is also a connection between obesity and Type 2 diabetes, although obesity does not lead necessarily to Diabetes. Type 2 Diabetes is a common disorder, affecting 5-10% of the population.

All type 2 diabetics produce insulin when diagnosed, and most will continue producing insulin for the rest of their lives. The main reason that causes the blood glucose levels remain high is the inability of muscle and fat cells to use all the insulin secreted by the pancreas. Thus, too little glucose in the blood is passed by these cells. This reduced action of insulin is called “insulin resistance.”

Symptoms of type 2 diabetes are less pronounced and this is the reason to consider this type of diabetes more “soft” than Type 1. The Type 2 Diabetes should be taken seriously, although its symptoms can remain undetected for a long time, since it can seriously put at risk the health of the individual.

This diabetes type can be controlled with help of Glucophage tablets.

Gestational Diabetes

Gestational diabetes is a condition that affects suddenly non-diabetic women who become pregnant.

In gestational diabetes, the woman develops diabetes only during pregnancy because it produces an insufficient amount of insulin for her and her baby.

At the end of pregnancy, women return to their normal state of insulin production. This is because, this time, the placenta produces substances that block the action of insulin, which can cause an elevation of glucose.

But we need not be alarmed. This is a temporary situation in your life and your baby will develop normally if followed all recommendations of your doctor.

At the end of pregnancy the woman back to its normal state and will experience the exciting task of being a mother.

Risk Factors

– Age over 30 years;
– Obesity or excessive weight gain during pregnancy;
– Close relatives with Diabetes;
– Pregnancy previous baby weighing more than 4 kg at birth;
– abortion or fetal death before (non-enlightened);
– Treatment for “High Pressure”;
– Diabetes present in previous pregnancies;
– Presence of glucose in the urine.

Symptoms

– Urinating too
– Have excessive thirst
– Eating too
– Loss or extreme weight gain
– Fatigue, weakness and despondency.

Note: Gestational diabetes can be present even without the woman has any of these symptoms

Consequences of increased abnormal glucose for mother and baby

– Macrosomia – the child may be born and grows much weighing more than 4 kg;
– Childbirth Caesarean depending on the size of the child;
– Baby with hypoglycemia (low blood sugar);
– Fetal death in utero;
– frequent urinary infections in pregnancy;
– Premature birth due to excess of amniotic fluid in utero, even causing an exaggerated increase in stomach and body weight.

When gestational diabetes is diagnosed, it would be ideal to accompany a team of doctors obstetrician and endocrinologist, nutritionist and nurse. Otherwise, follow all instructions of your doctor.

Keeping glucose levels in normal, pregnant women avoid all the consequences of gestational diabetes.

Diabetes Mody

Diabetes type MODY (maturity-onset diabetes of the young) is a subtype of diabetes mellitus, characterized by early onset (usually under 25 years of age) and autosomal dominant (determined by at least three generations). Corresponds to a primary defect in insulin secretion, associated with dysfunction in the pancreatic ? cell.

Thus, necessary prerequisites for the diagnosis of diabetes MODY are:

Diagnosis performed before 25 years of age in at least one family member.

Autosomal dominant with at least 3 generations affected by diabetes.

Capacity control without diabetes to insulin action (and without developing ketosis) for a period of at least 2 years and significant amounts of peptide C.

According to various studies, diabetes type MODY, correspond to a monogenic condition of high penetrance, although with high heterogeneity at the clinical level. This heterogeneity allowed to date the determination of various subtypes of diabetes Mody, knowing currently six genes responsible for disease development, allowing their classification into six distinct subtypes: MODY 1, MODY 2, MODY 3 MODY 4, MODY MODY 5 and 6. It is important to note that there must be other genes, as yet unidentified, that are responsible for the development of other subtypes of MODY diabetes, commonly referred to as MODY X.

Diabetes type MODY, first described in 1974 reaches about 2% (1-5%) of all diabetic patients. Admitting that in Portugal there are 600,000 diabetic patients, approximately 12,000 of these patients would have that type of diabetes. However, most of these patients end up being classified as diabetes type 1 or 2, depending on the subtype of MODY. It should be suspected in patients diabetes MODY considered as type 2 diabetics with onset of the disease at an early age and relative or heavy burden on patients classified as type 1 diabetes, but controlled with low doses daily insulin or peptide levels C dos?veis.

It is known that diabetes type MODY have different developments, depending on the subtype involved in genetic characterization increase the information concerning the prognosis. Besides allowing the stratification on the likelihood of the development of late complications of diabetes, the genetic characterization of subtype of MODY in question may have implications for the therapeutic regimen to adopt and the level of demand relative to metabolic control.

The genetic study of other family members (diabetic or not) allows the identification of family members in which the mutation is present. In members of the family in which the mutation is present but has not developed diabetes, particularly in relatives younger ages, a greater incentive to adopt healthy lifestyles could have implications in terms of delay in disease development.